Stites, E. C., Aziz, M., Creamer, M. S., Von Hoff, D. D., Posner, R. G., & Hlavacek, W. S. (2015).
Use of mechanistic models to integrate and analyze multiple proteomic datasets.
Biophysical journal, 108(7), 1819-1829.

PMID:25863072  DOI: 10.1016/j.bpj.2015.02.030


This model describes the binding and phosphorylation of EGFR by many different proteins which can bind to six different receptors. This ModelBrick describes the binding of proteins to the 1092 receptor.

The curated model

VCell: reaction diagram VCell: reaction diagram


  VCell ModelBrick CM_PM25863072_Y1092.vcml Exported from VCell
  BioNetGen file CM_PM25863072_Y1092.bngl Exported from VCell


Bushrah Khan, Riley Steinberg, Michael Blinov