Curated Model: HIV latency described by HIV proteins’ interactions and the innate immune response
Aguilera, L. U., & Rodríguez-González, J. (2014).
Studying HIV latency by modeling the interaction between HIV proteins and the innate immune response.
Journal of theoretical biology, 360, 67-77.
Studies have determined that HIV latency is influenced by the innate immune response carried out by cell restriction factors that inhibit the postintegration steps in the virus replication cycle. This mathematical model combines deterministic and stochastic approaches to analyze the interactions between HIV proteins and the innate immune response.
|VCell: Reaction Diagram|
|VCell curated model||CM_PM24997239.vcml||Designed with VCell|
|SBML||BIOMD0000000573.xml||Exported from BioModels database|
John Albanese, Michael Blinov