PDGF Regulated Activation of Src
Rangamani, P., Lipshtat, A., Azeloglu, E. U., Calizo, R. C., Hu, M., Ghassemi, S., … & Iyengar, R. (2013).
Decoding information in cell shape.
Cell, 154(6), 1356-1369.
This model represents the activation of Src kinase, which is stimulated by the growth factor PDGF. Protein tyrosine phosphatase (PTP) catalyzes Src activation, while activated Csk modulates the rate at which Src deactivation takes place.
|SBGN visualization||VCell: Reaction diagram||VCell: Pathway diagram|
|VCell curated model||CM_PM24034255.vcml||designed with VCell|
|GraphML||CM_PM24034255.graphml||exported from VANTED (SBGN-ED)|
|SBGN-ML||CM_PM24034255.sbgn||exported from VANTED (SBGN-ED)|
John Albanese, Michael Blinov