ModelBrick1: Cut-out Switch Rab5 activation
Del Conte-Zerial, P., Brusch, L., Rink, J., Collinet, C., Kalaidzidis, Y., Zerial, M., & Deutsch, A. (2008). Membrane identity and GTPase cascades regulated by toggle and cut-out switches. Molecular Systems Biology, 4.
This ModelBrick from the publication, “Membrane identity and GTPase cascades regulated by toggle and cut-out switches” describes Rab5 undergoing cycles of GTP binding and hydrolysis. The authors propose that Rab conversion is operated by a cut-out switch controlled by Rab7.
|Vcell: Simulation||SBGN visualization|
|VCell ModelBrick||download model (.vcml)||Designed with VCell|
|SBML||Exported from VCell|
|GraphML||CM_PM18628746_MB1.graphml||Created with VANTED (SBGN-ED)|
|SBGN-ML||CM_PM18628746_MB1.sbgn||Exported from VANTED (SBGN-ED)|
Maria Heredia, Michael Blinov