Tyson, J. J., Chen, K. C., & Novak, B. (2003).
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.
Current opinion in cell biology, 15(2), 221-231.
This ModelBrick from the article, “Sniffers, buzzers, toggles and blinkers…” is a toggle switch that describes mutual inhibition, where the response element (R) inhibits a protein E, and E promotes the degradation of R. R and E are mutually antagonistic.
|VCell ModelBrick||download model (.vcml)||Designed with VCell|
Michael Blinov, John Albanese