Tyson, J. J., Chen, K. C., & Novak, B. (2003).
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.
Current opinion in cell biology, 15(2), 221-231.
This ModelBrick from the article, “Sniffers, buzzers, toggles and blinkers….” is a one-way switch describing mutual activation where the response element (R) activates protein E by phosphorylation, and EP enhances the synthesis of R.
|VCell ModelBrick||download model (.vcml)||Designed with VCell|
Michael Blinov, John Albanese