Protein Phosphorylation: Sigmoidal
Tyson, J. J., Chen, K. C., & Novak, B. (2003).
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.
Current opinion in cell biology, 15(2), 221-231.
This ModelBrick from the article, “Sniffers, buzzers, toggles and blinkers…” describes protein phosphorylation and dephosphorylation reactions governed by Michelis-Menten kinetics, yielding a sigmoidal signal-response curve.
|SBGN visualization||Publication: Simulation|
|VCell ModelBrick||download model (.vcml)||Designed with VCell|
|SBML||CM_PM12648679_MB2B.xml||Exported from VCell|
|GraphML||CM_PM12648679_MB2.graphml||Designed with yED|
|SBGN-ML||CM_PM25628036_MB2.sbgn||Converted with ySBGN|