ModelBrick1: cI represses LacI transcription and translation


Elowitz, M., & Leibler, S. (2000). A synthetic oscillatory network of transcriptional regulators. Nature, 403(6767), 335-338.
PMID:10659856  DOI: 10.1038/35002125


This ModelBrick describes changes in the concentration of protein LacI under the transcriptional repressor activity of cI. The simulation consider a change in the species concentration compare to original Model to better represent the activity of the protein repressor cI over the transcription, and translation of LacI. The initial concentration of the repressor protein has been set at 150 molecules/um3 while the other two species were set at 0 molecules/um3.


Vcell: reaction diagram Vcell: Simulation SBGN visualization


VCell curated model CM_PM10659856_MB1.vcml Designed with VCell
SBML Exported from VCell
GraphML CM_PM10659856_MB1.graphml Exported from VANTED (SBGN-ED)
SBGN-ML CM_PM10659856_MB1.sbgn Exported from VANTED (SBGN-ED)